Derek Zoolander and Hansel McDonald are back in action in the first full-length trailer for "Zoolander 2."

Ben Stiller and Owen Wilson return as the world-famous supermodels, who discover they're now jokes in a fashion industry that's left them far behind. But when an Interpol agent (Penelope Cruz) approaches them for help in uncovering who's killing the world's most beautiful people -- Justin Bieber among them -- Derek sees a path to returning to the top.

Directed by Stiller from a script he wrote with Justin Theroux, "Zoolander 2" also stars Christine Taylor, Kristen Wiig and Will Ferrell, with a long line of celebrity cameos. The film opens Feb. 12.