I was just recently doing a bit for Entertainment Legends Revealed about The Life of Riley, William Bendix's radio and television sitcom that included the catch phrase, "What a revoltin' development dis is!"
Naturally, that has become one of Ben Grimm, the Thing's catch phrases, as well.
Ben has also taken on quite a few mannerisms of Jimmy Durante.
The whole "using old (and usually dead) celebrities as the personalities for characters" approach is used in cartoons frequently (most prominently right now, Seth McFarlane is getting good usage out of the public personalities of Rex Harrison and Paul Lynde), but besides the Thing, can you think of other notable comic book characters whose personalities are derived from celebrities, alive or dead?
Parodies don't count!