"Weird Al" Yankovic will lead the voice cast of Disney XD's "Milo Murphy's Law," the new animated comedy from "Phineas and Ferb" creators Dan Povenmire and Jeff “Swampy” Marsh.
The legendary music satirist will also sing the opening theme and perform original songs as the title character.
Yankovic will play Milo, the fictional great-great-great-great-grandson of the Murphy's Law namesake and the personification of Murphy's Law, which states that anything that can go wrong will. Still, optimistic Milo always tries to make the best of the cards he's dealt.
The voice cast also includes as Sabrina Carpenter and Mekai Curtis as Milo's friends Melissa Chase and Zack Underwood; Christian Slater as Milo's foe, school crossing guard Elliot Decker; Vanessa Williams as Zack’s mom Eileen Underwood; Sarah Chalke as as science teacher Mrs. Murawski; Jemaine Clement as popular TV character Dr. Zone; Mackenzie Phillips as Principal Milder; Chrissie Fit as classmate Amanda Lopez; Dee Bradley Baker as Milo's dog Diogee; and Michael Richardson as Coach Nolan Mitchell.
"Milo Murphy's Law" debuts this fall in Disney XD.