Co-creator Ryan Murphy has unveiled the opening credits for his upcoming comedy-horror series "Scream Queens." Unsurprisingly, there's a lot of screaming. A lot.

Set in elite sorority house, the anthology series revolves around a college campus rocked by a series of murders by a killer in a devil costume.

Debuting Tuesday, Sept. 22, at 8 p.m. ET/PT on Fox before moving to its regular time slot at 9 p.m., "Scream Queens" stars Jamie Lee Curtis, Emma Roberts, Lea Michele, Abigail Breslin, Keke Palmer, Skyler Samuels, Nasim Perdad, Billie Lourde, Oliver Hudson, Diego Boneta, Glen Powell and Lucien Laviscount, with guest appearances by Ariana Grande and Nick Jonas.