Vampirella assumes the role and obligations of the Drago, joining the Kabala clandestine organization of supernatural creatures. When a strange, rabies-like plague spreads through the slums of Sao Paolo like wildfire, infecting victims with homicidal fury, the Kabal calls upon Vampirella to capture the disease's murderous creator -- one of The Accursed, a human condemned to eternal life for his sins: the fabled Dr. Faustus.