Principal photography has officially begun on Joe and Anthony Russo's latest film Cherry, the brothers' first project since beginning their extensive work with Marvel Studios in 2013, reuniting with longtime Marvel Cinematic Universe collaborator Tom Holland.

The upcoming film is an adaptation of the bestselling novel of the same name, telling the tale of an Iraq War veteran, portrayed by Holland, suffering from post-traumatic stress disorder and robbing banks upon his return home to support his torturous opioid addiction. The project was first announced in March, with Holland attached to star, as the Russos were deep into post-production on Avengers: Endgame.

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"We were drawn to Cherry given our personal experience from Cleveland, as well as the important need to share stories like these," the Russos said in a joint written statement. "As Cleveland natives ourselves, it means a lot to us to be able to film in our hometown. We shot the exteriors for Winter Soldier here, we are excited to return home to our roots."

The Russos first worked with Holland in 2016's Captain America: Civil War, casting the young actor as Spider-Man. The filmmakers reunited with him in the subsequent ensemble films Avengers: Infinity War and Endgame. For their first film outside of the MCU in six years, the trio's next collaboration is shaping up to be a significant departure from their acclaimed superhero fare.

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Directed and produced by Joe and Anthony Russo, Cherry stars Tom Holland, Bill Skarsgard, Jack Reynor, Forrest Goodluck, Jeff Wahlberg, Michael Gandolfini and Kyle Harvey.