Robert Langdon is humanity's final hope in the teaser trailer for "Inferno," director Ron Howard's adaptation of the Dan Brown novel of the same name.

Tom Hanks reprises his "Da Vinci Code" and "Angels & Demons" role as famed symbologist Robert Langdon, now on a trail of clues tied to Dante himself. When Langdon wakes up in an Italian hospital with amnesia, he teams with physician Sienna Brooks (Felicity Jones), whom he hopes will help him recover his memories. Together, they race across Europe -- and against the clock -- to foil a deadly global plot.

Also starring Irrfan Khan, Omar Sy, Sidse Babette Knudsen and Ben Foster, "Inferno" opens Oct. 28.