WARNING: The following contains spoilers for "The Face Behind the Glass," the fourth episode of The 100 Season 6.

The inhabitants of the alien world of Sanctum have been acting strangely suspicious ever since their introduction early in Season 6 of The 100. Having colonized the faraway planet approximately 200 years ago, the settlers exhibit strange pseudo-religious customs and have a close-knit society that resembles a cult. Now, in the latest episode, a big plot twist regarding Sanctum's inhabitants spells a completely different kind of trouble for the post-apocalyptic series' main characters.

The residents had initially planned to refuse Clarke and her fellow survivors safe harbor, as they prepared for a ritual known as a naming ceremony. But after discovering Clarke possessed blackened blood, known by Clarke as "Nightblood," granting her immunity against lethal levels of radiation, Sanctum quickly changed their mind, noting that the blood denoted royalty among them and allowed them to stay. However, as a young woman named Delilah proceeded with her naming ceremony, it became clear that Sanctum's newfound hospitality comes with sinister intentions.

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After a day of effusive celebrations encompassing the entire community, Delilah is brought into the depths of Sanctum, away from everyone but the village leaders for her naming ceremony. Upon emerging and reuniting with her new lover, Jordan Green, Delilah no longer recognizes him and now goes by the name Priya, immediately worrying Jordan and the other visitors from Earth. Even more troublesome, the leaders have taken an increased interest in Clarke and her Nightblood.

Throughout the latest episode, Clarke is examined thoroughly by a young, handsome doctor who repeatedly asks if anyone else in her group possesses Nightblood. The doctor attempts to seduce Clarke, only for his plans to become exposed. Tranquilizing Clarke, leading to her own imprisonment by the leaders, the reason for their interest in her blackened blood is nightmarishly revealed.

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Deep within the recesses of Sanctum, Clarke discovers that those with Nightblood can have someone else's consciousness transferred into a new host body. In a creepy lab filled with the skeletons of previous host bodies, the Sanctum leaders reveal that this process has kept the founding members of the colony alive in different hosts for over 200 years, and Clarke is the latest unwilling participant. In the closing moments of the episode, the transfer into Clarke is completed, her body now possessed by the consciousness of a woman named Josephine.

Jordan Peele's award-winning horror film Get Out saw the community of a remote upstate New York town implant the minds of aging members into younger, African-American bodies as a means to stay young and essentially immortal while the consciousness of their victims existed powerless in a realm known as the Sunken Place. The 100's variation on this trope removes the racial undertones, though the first visible victim in Sanctum, Delilah, is similarly African-American. Continuing with the post-apocalyptic series' themes that no welcoming community can be trusted, it is unknown what exactly has become of Clarke or Delilah's own consciousness after the transfer but presents the long-running CW series with a new insidious threat with friendly faces now under control of those with their own sinister designs. And when the Sanctum leaders learn that only Madi remains as a Nightblood within the visitors from Earth, they may not be as welcoming to Bellamy and the others.

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The 100 airs on The CW Tuesdays at 9 pm ET/PT. The series stars Eliza Taylor, Paige Turco, Marie Avgeropoulos, Bob Morley, Henry Ian Cusick, Lindsey Morgan, Richard Harmon and Tasya Teles.