Supergirl's Lena Luthor -- played by Katie McGrath -- hasn't exactly in the best following the demise of her half-brother, classic Superman villain Lex Luthor. But with Jon Cryer's Lex set to return in the Arrowverse's highly-anticipated "Crisis on Infinite Earths" crossover event, it begs the question of whether or not Lena seeing her brother again could help soothe her anger. According to McGath herself, however, it may not be that simple.

While sitting down with TVLine, McGrath was asked if the revelation that Lex is alive in Crisis could change Lena's perspective on things. "Well, you're supposing that he's going to be fine," she answered.

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"It's the crossover, so anything can happen," McGrath continued. "There are five episodes to tell that story, so we don't know what's going to happen. It's a whole new idea, a whole new world, so any presumptions are maybe misplaced."

In Supergirl, McGrath's Lena assumes control of Lex's company and attempts to atone for her half-brothers misdeeds. Meanwhile, she develops a bond with both Melissa Benoist's Kara Danvers and Supergirl herself (unaware they are the same person).

The relationship between Lena and Supergirl soon became rocky, with the younger Luthor sibling beginning to distrust the Girl of Steel. Lena ultimately killed Lex following his escape from prison, but not before he revealed to her that Kara -- one of her closest confidants -- is, in fact, Supergirl.

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Airing Sundays at 9 p.m. ET/PT on The CW, Supergirl stars Melissa Benoist as Kara Danvers, David Harewood as Martian Manhunter, Mehcad Brooks as Jimmy Olsen and Chyler Leigh as Alex Danvers.

"Crisis on Infinite Earths" begins Sunday, Dec. 8 at 8 p.m. ET/PT on Supergirl, then continues in Batwoman on Monday, Dec. 9 at 8 p.m. ET/PT and in The Flash on Tuesday, Dec. 10 at 8 p.m. ET/PT. After the winter hiatus, the crossover will conclude on Tuesday, Jan. 14 in Arrow at 8 p.m. ET/PT and in DC's Legends of Tomorrow at 9 p.m. ET/PT.