The world of Spider-Gwen, as the Gwen Stacy Spider-Woman is known, is a cornucopia of alternate versions of Marvel characters. From the beginning, there was a steady stream of supporting characters, like Frank Castle and Mary Jane Watson. Cameos like Yancy Street beat cop Ben Grimm were to trickle in as necessary.
There are a few versions that have been more exciting than others. Some have been enough of a departure from the norm to show how clever the creators are in crafting the world of Earth-65. It sometimes seems bleaker for its lack of a great number of heroes like Spider-Gwen. However, with all of the cameos that have yet to pop up, hope should spring eternal.
10 Baron Blood
Baron Blood showed up in a comic book retelling of an adventure that Captain America found eerily accurate. Artist Steve Rogers somehow tapped into her adventures to chronicle them in comic books.
What's so exciting about this Baron Blood is that he's Prince. It's not the first time that the music legend has graced a comic, but it's the first time that he's tried to seduce a superhero. Baron Blood is possibly not on Earth-65, but so far it should be considered that he is.
9 The Wasp
Janet Van Dyne has only been seen once, and then it was an advertisement. She was mentioned in Spider-Gwen's "handbook entry." She is the one that designed her web-shooters, assumably using her Wasp's sting as a guide.
She was the Wasp on Earth-65, as the advertisement uses her image in a Wasp headpiece. Given that she designed something for Gwen, she possibly designed stuff for other heroes that haven't been seen yet. It also opens up the door for other heroes being active on Earth-65.
8 Felicia Hardy
Fans see Felicia Hardy with her band the Black Cats. She invites Matt Murdock to her show to get revenge for her father's murder. Like the more familiar counterpart, this Felicia Hardy is a skilled thief, getting into Fisk Tower without being detected.
Felicia set out to kill Matt Murdock, which put Gwen in an odd position. To stop a murder, she had to protect the life of one of the evilest men in New York. Felicia Hardy ended up going to jail, her success not sparing her from the consequences of her actions.
7 Cindy Moon
On Earth-65, Cindy Moon is never bitten by a radioactive spider. She did go on to join S.H.I.E.L.D. and save Jesse Drew from radiation poisoning she and Drew then formed the criminal organization SILK. She even releases the spider that gives Gwen Stacy her super-powers.
She became a thorn in the side to Gwen, her regular Marvel counterpart, and the regular Jessica Drew. She stole Gwen's teleporter to steal technology from the mainstream Marvel Earth. Fortunately, the three spider-women managed to stop her with the help of Jesse Drew.
6 The Watcher
Anytime Uatu the Watcher shows up in Spider-Gwen, it's a fun scene. This Watcher is bored in his duties and tries in vain to interfere and make things interesting. Unfortunately, he fails and even continues to neglect his duties to observe.
This Watcher uses a television set to perform his duties, most likely to give him a break from omniscience. He's confronted by his Earth-8 counterpart, who watches a reality much more idealistic where Miles Morales and Gwen Stacy married. The events on Earth-65, where Gwen has bonded with Venom, are endangering Earth-8.
5 Matt Murdock
Matt Murdock is Gwen's most dangerous opponent. He runs Kingpin's criminal organization. Most dangerously, he commands an army of Ninjas.
He gets Gwen into a position where she has to work for him. His manipulation even extends to Cindy Moon's SILK. Most of all, his calculating demeanor never shakes. He lives up to the reputation his heroic counterpart has as "the man without fear."
4 She-Hulk
She-Hulk first appears as a professional wrestling champion for the UCWF. She is also seen on a magazine cover before she crosses paths with Gwen in the justice system as her lawyer.
It's there that She-Hulk indicates how powerful she is. She tells Gwen that it took years to transform her body into a mass of muscle. She also reveals that her emerald hue is just body paint. While initially it was assumed that she was superhuman, it looks like it's not so.
3 Reed Richards
Gwen, Silk, and Jessica Drew needed a way to follow Cindy Moon to the main Marvel Earth. When they started looking for Earth-65's Reed Richards, they found him someplace unexpected. He was on a playground. Reed Richards was just thirteen years old.
Reed is the same genius that he is across the multiverse and more than a little condescending to adults. He is good at heart, which on Earth-65, is a refreshing discovery.
2 Captain America
Samantha Wilson is a departure from Captain America that fans are used to. She instantly commands awe and respect as soon as she enters the room. While she works for S.H.I.E.L.D., she does so out of an obligation to do what's right and correct the missteps that have happened in the seventy-five years she was gone.
While volunteering at the James Barnes VA Hospital, she discovered Steve Rogers, whom she knew from the Super-Soldier Program, had been illustrating her adventures in the multiverse, somehow tapping into her adventures in his dreams.
1 Mister Murderhands
In the regular Marvel Universe, he's referred to as Wolverine. Having been to the regular Marvel Earth, Gwen even insists that everyone call him Wolverine. However, this Wolverine lives up to the name of Mr. Murderhands.
Logan was cursed to do penance for the murders that he committed and Weapon X then took away his memories to turn him into the perfect killer. Fortunately, S.H.I.E.L.D. has Logan teamed up with Shadowcat. She's doing penance for working with Weapon X by keeping Logan from living up to the Murderhands name too much.