Ryan Reynolds and Ben Mendelsohn Can't Lose in 'Mississippi Grind' Trailer

A24 has debuted the first trailer for "Mississippi Grind," the upcoming gambling drama that stars Ryan Reynolds and Ben Mendelsohn as a pair of unlikely friends hoping for a big win.

Gerry is a talented, but struggling poker player about to be swallowed up by his unshakeable gambling habit. But his luck begins to change after he meets the young, charismatic Curtis. Gerry convinces his new lucky charm to hit the road with him, towards a legendary high stakes poker game in New Orleans. The highs and lows unveil the duo’s true characters and motivations, and an undeniable bond forms between them.

Directed by Anna Boden and Ryan Fleck, the film also stars Sienna Miller, Analeigh Tipton, Alfre Woodard and Robin Weigert. "Mississippi Grind" opens Sept. 25.

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