"I wanted to try applying the lessons learned from the Wednesday Comics experience to a different subject, here finding a source which would be difficult to illustrate as a page of comics, given that there is very little suggested action. I find that with the format of Wednesday Comics (which is really the traditional Sunday Comics page), one must condense the plot and action to the briefest yet most vivid bursts of information available-- there is a lot of space on the page for the illustrations to really overwhelm the reader/viewer, but there isn't a lot of space for story development in the sense of how we'd develop a plot or work up dialogue for a typical comic book page. In a comic book, one page may be well drawn or well written, but it is still just a single facet of a larger whole. One page can be preceded or followed by another, but no one page carries the entire weight of the sustained narrative. The Wednesday Comics single page format forces the artist to create a story unit which may well be part of a larger storyline, however it still must be able to stand alone."
(Also, click the link to check out his really awesome Dune artwork).