The Merc with a Mouth has a knack for making more enemies than friends. Now, in part three of "The Marvel Universe Kills Deadpool," that uncanny ability is coming back to bite Wade Wilson in a big, BIG way in our preview for next week's Despicable Deadpool #299.

It isn't just Captain America, the two Hawkeyes and the Deadpool Task Force that are teaming up to bring Wade in, though. Writer Gerry Dugan and artist Mike Hawthorne are along for the ride, as well, and judging by what this creative team is putting Deadpool through, you'd think they hate him every bit as much as the rest of the Marvel Universe.

RELATED: The Avengers Have Recruited a Familiar Face to Hunt Down Deadpool

Check out the issue’s solicitation text and CBR’s exclusive preview below.

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DESPICABLE DEADPOOL #299

  • GERRY DUGGAN (W) • MIKE HAWTHORNE (A/C)
  • THE MARVEL UNIVERSE KILLS DEADPOOL Part 3
  • It’s the second-to-last skirmish in the saga of the DESPICABLE DEADPOOL, and now it’s not just enemies after him, but everyone. Self-deprecation, self-defeat and self-destruction saddle up as Deadpool dives deeper into despicability! Plus, what are you gonna do, stop reading at #299?
  • 32 PGS./Parental Advisory …$3.99
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KEEP READING: Deadpool Pays Unexpected and Heartbreaking Homage to Alan Moore