In the world of Japanese anime, family usually plays an important role, regardless of genre. In anime shows of all types, a character's immediate family will have a huge impact on their lives, often for the better. Some characters have terrible parents, but others get along perfectly with their upstanding parents or their beloved brothers and sisters.
In particular, anime sisters are often expected to be friendly, helpful people, and rarely do anime sisters subvert those expectations. Anime fans have met plenty of good-hearted sister characters over the years, and the kindest, sweetest, and most compassionate of them often become their respective series' best characters. Their siblings are highly fortunate to have them around.
10 Nezuko Kamado Has Her Brother's Back (Demon Slayer)
Although Nezuko Kamado cannot speak and is often asleep or hidden away, Demon Slayer fans are certain that she's one of the best anime sisters out there. Not only is Nezuko a fine melee fighter, but she will also always fight to defend humanity and defeat evil, not for her own sake.
Nezuko, like Tanjiro, is a naturally kind, helpful, and compassionate person who just wants others to be safe and happy in these dark times. She is also wonderfully innocent and playful. It's no wonder Zenitsu Kamado was drawn to this kind-hearted demon girl.
9 Yotsuba Nakano Wants To Help Out (The Quintessential Quintuplets)
The five identical Nakano sisters may have the same face, but they certainly don't have the same personality. Nino Nakano is a total tsundere, while Ichika has a big sister mentality. Then, there's Yotsuba, the playful and energetic one who always wants to have fun.
Yotsuba is a bit flaky at times, but she is also very kind and is always eager to help other people, most of all her four sisters or her tutor Futaro. She sometimes lets Futaro down with her bad grades, but she's trying, and she would never do anything to hurt him, either. She hopes everyone can be as happy as she is.
8 Reina Aharen Looks After Her Brother & Sister (Aharen-San Is Indecipherable)
Reina Aharen is a total kuudere, a quiet, calm lover who only shows their romantic side to the right person. She is also the oldest of three siblings at home, something that her new friend Raido discovered when he visited one evening.
Reina works hard for her younger brother and sister and often cooks for them, and for that matter, she often shares her lunches with Raido, too. Aside from preparing meals, Reina also shows her kind side by providing emotional support to anyone who might need it, such as her dandere friend Oshiro. Everyone can count on her.
7 Shikimori Is Everyone's Best Friend (Shikimori's Not Just A Cutie)
The pink-haired Shikimori is popular at her school for her good looks, her athletic prowess, and most of all, her sheer kindness and generous ways. Shikimori even comforted her would-be romantic rival, Kamiya, and befriended her, something only a truly kind anime character would do.
Shikimori gets along great with her boyfriend, Izumi, and their mutual friends, and while he finds her older brother Fuji annoying, they still respect one another greatly. Fuji has even been known to buy his little sister gifts in exchange for her kindness.
6 Shuna Can Brighten Anyone's Day (That Time I Got Reincarnated As A Slime)
Princess Shuna is another pink-haired little sister who wants nothing more than to make everyone around her happy, including her warrior brother, Benimaru. Shuna is also rather humble, being content to remain in the background while Benimaru and Rimuru assume a leadership role in Tempest city.
Shuna is a great cook and tailor, and she warmly shares cozy new outfits and luxurious meals with all her friends without asking for anything whatsoever in return. She even treats Rimuru like her own dress-up doll at times, and even if Rimuru finds the outfits ridiculous and refuses to wear them, it's all in good fun.
5 Tsuyu Asui Has Strong Empathy (My Hero Academia)
Tsuyu Asui is a highly empathetic, thoughtful, and practical student hero who always acts like the big sister she is. At home, Tsuyu helped look after her younger brother and sister, and at UA, she always has the well-being of her classmates in mind, too. Being a hero is about more than action.
Tsuyu is a sensitive and kind person who will quickly become upset if her friends betray her trust, and she might even burst into tears. This was the case after the Bakugo rescue mission, when the ultra-kind Tsuyu feared for her classmates' lives.
4 Shoko Komi Is Quiet But Sweet (Komi Can't Communicate)
The popular dandere Shoko Komi is revered as an aloof ice queen at her school, but she is not exactly a conceited wannabe princess. In fact, Shoko Komi has a communication disorder and is terribly lonely, while her little brother Shosuke merely chooses not to communicate.
Shoko is a very kind-hearted and generous person who is eager to build a social life for herself. Time and again, she graciously supported her classmates when they needed her and empathized with them, and she always returns the favors that Tadano, Najimi, and the others do for her.
3 Mirajane Strauss Defends All Her Guildmates (Fairy Tail)
Many of the kindest and sweetest anime sisters are also the eldest child, such as Mirajane Strauss. She is the oldest and strongest of the three Strausses, and all her guildmates look up to her as a beautiful, caring, and powerful guildmate who will always look after them.
Mirajane knows all about the values of kindness, and she even made it her personal philosophy. She once commented that loneliness will always teach people the virtue of kindness, and when she's around, no one will have to be lonely or miserable ever again.
2 Katarina Claes Adores Her Foster Brother (My Next Life As A Villainess)
Katarina Claes is an otome game villain turned hero. The original version of her was quite cruel to her foster brother Keith Claes, but the isekai version is a model sister who helped Keith grow up to be happy and well-adjusted instead. Thus, Keith is now quite close to her.
Katarina is boundlessly kind and generous toward not just her foster brother, but also her many new friends, including Maria Campbell herself. For both her sake and theirs, Katarina will say or do anything to look after her friends' well-being, and her shoulder is always free for someone to cry on.
1 Yor Forger Is A Compassionate Assassin (Spy X Family)
Even if she is a deadly assassin, the warm-hearted Yor Briar, now Yor Forger, is the best sister any anime character could ask for. She was like a mother to her much younger brother Yuri, so it's no wonder Yuri is totally obsessed with her. Yor worked tirelessly to keep her brother safe and happy growing up.
Today, Yor is still a generous, caring, and warm-hearted person who always puts others' needs first. She is also highly sympathetic and cares greatly for the emotional well-being of her foster daughter, Anya. Anytime Anya is even slightly upset, Yor will rush over to help.