WARNING: The following contains spoilers for Miles Morales: The End #1, by Saladin Ahmed, Damion Scott, Dono Sanchez-Almara and VC's Cory Petit, on sale now.
Set in a post-apocalyptic Brooklyn, Miles Morales: The End #1 jumps decades into the future. Over the course of the comic, there are a lot of hints dropped about the fates of some of Spider-Man's greatest allies, some of whom have not survived.
The first confirmed death is that of someone very close to Miles. The End opens with the title hero saving a father and daughter from monsters on the Brooklyn Bridge. Although he's still wearing his Spider-Man costume, Miles calls himself the Mayor/El Alcalde. After they get into Brooklyn -- which is safe from the outside world -- they're introduced to Maxine Lee, the deputy mayor. This is when it's revealed Miles' best friend, Ganke Lee, has died and Maxine is his daughter.
Created by Brian Michael Bendis and Sara Pichelli, Ganke first appeared in 2011's Ultimate Comics Spider-Man #2. Ganke is one of the first people with whom Miles shared the secret of his abilities, and he worked to both aid and abet his best friend. When the Ultimate Universe was destroyed, Ganke made his way over to Earth-616, where he's remained ever since.
The End doesn't get into the details of Ganke's death. Miles remarks that Ganke was "a hero," and the statue dedicated to him calls him the "Protector of Brooklyn." The book also reveals Ganke played a major role in making Brooklyn safe and keeping people alive during the apocalypse.
Ganke isn't the only one whose fate is disclosed. A short time later, Miles goes to aid a caravan from New Jersey against the One America Army. During that confrontation, Spider-Man encounters Captain Last who is decked out in garb inspired by Captain America. He even has the hero's vibranium shield -- though it's cracked and chipped -- and at some point took a version of the Super Soldier Serum.
Seeing the bandit dressed like Captain America angers Miles, who declares, "He was my friend. And I'm gonna make you sorry as Hell you had the gall to dress up as him!" Just which Captain America Miles is referring to isn't totally clear, though it seems likely it's Steve Rogers due to the gear the imposter's sporting and the association he has with Brooklyn.
The final reference occurs after Miles beats the One America Army. Miles walks up to a young man with the caravan named Bilal and it's revealed he's the son of Kamala Khan/Ms. Marvel. Miles and Kamala have a particularly long history and are key members of the Champions, a group of younger superheroes. Bilal shares that Kamala is, in fact, still alive, and Miles expresses his desire to see her again, though he never does.
Miles has a lot of friends in the Marvel Universe that don't get talked about or referenced in this story. However, the nature of this post-apocalyptic world makes it quite likely they're not all still kicking around. The future of The End may be bleak, but it's also one in which the hope inspired by heroes past and present keeps humanity going, even in its darkest days.