WARNING: The following contains spoilers for Loki Episode 3, "Lamentis," streaming now on Disney+.
In the Loki series, Tom Hiddleston's God of Mischief thinks he's still meant to be the ultimate puppet master. It's why Sylvie, the Variant Loki, can't stand him in their temporary alliance. She hates how big his ego is and that he's so self-assured even with the deck stacked against him. However, while it seems like Loki has made a breakthrough in swaying her to his side on Lamentis-1, he might have already been defeated by this Enchantress.
Sylvie definitely doesn't seem like your typical Loki. With her mind-control powers and ability to skew people's perceptions and realities, it feels like she's really the modern Enchantress. So much so, she calls her abilities "enchanting" people, which Loki balks at the prospect of.
He doesn't think her powers work on him because his mind's stronger than other agents in the Time Variance Authority. In his eyes, only lesser beings are susceptible to her enchanting. However, Loki fell prey to the Mind Stone when he used the scepter in The Avengers. It's canon in the Marvel Cinematic Universe that it played on his mentality, urging him to become corrupt and seize power. Thus, his mind isn't the fortress he thinks it is. And as a result, he might already be enchanted.
Lamentis-1 could be Sylvie setting him up, building a construct after sensing he has PTSD from genocide. When she initially mind-probed him, it's easy to see her figuring out how broken Loki is, given how his actions led to the annihilation of Asgard. It'd be perfect fodder to use against him, and a major clue comes in how he's trying to save innocents as Lamentis-1 crumbles.
It could be Sylvie breaking him down to find out where he's hidden the real TemPad or, worse yet, to possess his body. It'd be a nice fake-out and form of misdirection Loki has done time and time again, impersonating Thor and Odin. As such, it would give Sylvie the perfect form to infiltrate the TVA. Sylvie/Loki can corrupt other agents like Mobius, meet the Time Keepers per the deal agreed upon with Mobius or even blow the place up to create branched timelines and alternate realities. In that sense, Sylvie can start a multiversal predicament by relying on the best person she can -- herself, or at least a version of it by using Loki as a patsy.
Manipulating Loki through sympathy would also match what she told him when they boarded the Lamentis-1 train about plans, steps and levels. She mentions simplicity in disguise works. With that in mind, this could be the most well-orchestrated ruse any Loki has ever pulled off.
Loki stars Tom Hiddleston, Owen Wilson, Gugu Mbatha-Raw, Wunmi Mosaku, Sophia Di Martino, Richard E. Grant, Sasha Lane and Eugene Cordero. New episodes air Wednesdays on Disney+.