MCU fans know that everyone's favorite web-slinger and the Sorcerer Supreme have had a handful of encounters. From Avengers: Infinity War to Spider-Man: No Way Home, these two dissimilar do-gooders have found themselves fighting side by side more often than expected. However, this is a relatively common team-up in the world of Marvel Comics.

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Both Spider-Man and Dr. Strange have been in the game for a long time. It's only natural for the two New York-based heroes to cross paths every now and then. Many fans are unaware of how close they are. From world-saving missions to personal favors, these two heroes come together frequently. There's plenty to learn about their friendship.

10 When Spider-Man And Dr. Strange First Met

Spider-Man And Dr. Strange Vs. Xandu

In Amazing Spider-Man Annual (1964) #2, Xandu, a master magician, seeks to combine the two pieces of the Wand of Watoomb. Dr. Strange stands against him to contain the artifact's power. Spider-Man also stumbled across Xandu's plot, arriving in time to help Dr. Strange stop Xandu. After some quick thinking and fast-paced teamwork, Xandu was defeated and they returned the wand into Strange's possession. Spider-Man's actions that night endeared him to the good doctor, so he considered Spider-Man a friend and ally from that day on.

9 Spider-Man Helps Dr. Strange With The Werewolf's Cure

Clea Explains Curse to Spider-Man

Marvel Team-Up (1972) #80 is one of Spider-Man and Dr. Strange's more peculiar tales. After being cursed with lycanthropy, the overwhelming will of the werewolf left Dr. Strange erratic and uncontrollable. Luckily, Spider-Man was swinging by Central Park during Stephen's rampage.

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Spider-Man was able to deduce the identity of the werewolf and, with the help of sorceresses Clea and Satanna, pinned Dr. Strange down and cured him of his curse. For all of Stephen Strange's power, even he is sometimes overwhelmed by the darker side of the mystic world. Fortunately, he can always count on Spider-Man to lend a hand.

8 The New Avengers

New Avengers Offer Help to Dr. Strange

In the aftermath of the superhero Civil War, those who fought alongside Captain America were forced into the shadows to avoid the repercussions of the Superhuman Registration Act. This is seen in Civil War #7. Stephen Strange, while a neutral party during the Civil War, offered sanctuary to those heroes.

This included Spider-Man, Luke Cage, Jessica Jones, Iron Fist, Wolverine, Clint Barton (as Ronin), and Spider-Woman. Others would join their ranks, and all were welcome to take shelter in the Sanctum.  Together they faced down a slew of threats, from The Hand to the return of Agamotto.

7 Peter's Personal Mystical Physician

Spider_Man Gets Help From Dr. Strange

When Spider-Man faces a threat that goes beyond his spectacular abilities, he's made a habit of asking Dr. Strange to lend a hand. Whether it's a thug with a mystical artifact and a trip to the astral plane, Spider-Man knows he can count on Dr. Strange. On one occasion, in Amazing Spider-Man (1999) #42, Peter was dealing with a dimension-hopping kidnapper who was targeting the homeless. After coming to the doctor for help, Spider-Man gains access to the astral plane himself and rescues the victims.

6 Chance Encounters

Spider-Man And Dr. Strange Team Ups

Whenever Dr. Strange is in need of assistance, Spider-Man isn't always his first choice. Webs and quips just aren't going to cut it against the Dread Dormammu. Many times, like in their first meeting, Peter's involvement in Strange's adventures happened purely by coincidence.

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There are occasions where Dr. Strange sends out a mystic distress call for anyone nearby to come and aid him. More often than not, it's Spider-Man who picks up first. Despite magic being outside the wallcrawler's wheelhouse, he's frequently shown to be just what the doctor ordered.

5 Secret Identity Crisis

Dr. Strange Makes Everyone Forget Spider-Man's Secret

If fans have seen any promotional material for Spider-Man: No Way Home, then fans might recognize this event. When the world knew Spider-Man's secret identity, everything Peter feared would happen followed. Kingpin was after his family and there wasn't a thing he could do. Fortunately, in Amazing Spider-Man (1999) #641, Stephen Strange had a solution.

Strange, along with Iron Man and Mr. Fantastic, created an amalgamation of magic and science that caused everyone to forget Peter's secret identity. The only way for anyone to remember is if Peter reveals it to them.

4 Spider-Man Vs. Dr. Strange

Art of Spider-Man and Dr. Strange

In Spider-Man/Doctor Strange: The Way To Dusty Death, Xandu returns to achieve his goal of reuniting with his wife Melinda. Xandu brings her to the Death Dimension with him. Somewhat reflecting the first time the two heroes met, Spider-Man happens across Melinda and brings her to the Sanctum - just in time for Xandu to launch his attack.

Since Xandu was in his astral form, the villain possessed Spider-Man's body. Xandu combined the spider's powers with his mystic might to fight Dr. Strange. Their battle raged from Grand Central Station to the Death Dimension. Eventually, Peter returned to his body, and the two heroes once again stopped Xandu's misuse of magic.

3 Strange Let's Spider-Man Talk To A Spider

Spider-Man Talks to a Spider

In Doctor Strange (2015) #390, after a particularly challenging year in Stephen Strange's life, the doctor was rather sad. While trying to reconnect with Zelma, a friend of his, Dr. Strange gets a visit from Spider-Man. Unlike other times, this visit had nothing to do with magical threats or cosmic battles of good and evil.

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Instead, was a simple, friendly visit. During their brief chat, Peter drops hints that he'd like to talk to a spider and Dr. Strange obliges him. The conversation was a strange one, topics ranging from the different ways they shoot webs to the fleeting nature of life. Overall, Peter found the conversation pretty terrible.

2 The Pair Travel Through Time Together

Dr. Strange Guides Spider-Man Through Time

In Amazing Spider-Man (1999) #500, Dormammu launched an attack on earth. Dr. Strange enlisted the help of every available hero to stop him. During the battle, Strange and Dormammu are locked in a spell that would scatter them through every dimension - essentially killing them both.

Spider-Man tries to defend Stephen from Dormammu's forces. Unfortunately, Spider-Man also gets knocked into the spell. Luckily, the spider's intrusion changed the shape of the spell and flung the two heroes outside of time. In order to return, Peter had to be flung through his timeline, reliving his hardest battle and most devastating moments until he reached the present. Dr. Strange was there, in every step, to guide him home.

1 Dr. Strange Gives Spider-Man Time To Say Goodbye

Dr. Strange Let's Spider-Man See Uncle Ben

The death of Uncle Ben has always been a pivotal moment in Spider-Man's career. His death was the start of many things, including being the driving force in starting Spider-Man's life as a hero. Uncle Ben's death was the beginning of Spidey's guilt complex, and is what brings him grief on his darkest days.

After traveling with Peter through his history, Dr. Strange became familiar with what drives Spider-Man and how much Ben meant to him. So, in Amazing Spider-Man (1999) #500, Stephen gave Peter a chance to talk to his Uncle one final time, momentarily snatching him seconds from his death to help give Peter some peace over that night.

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