Three weeks ahead of its worldwide release, Marvel's Avengers: Infinity War is on a course to open with a domestic box office as high as $200 million.

As is custom for Hollywood studios, Disney's early projections are more conservative, but early industry estimates place the opening-weekend receipts in the $175 million to $200 million. Those figures will more than likely climb as excitement builds with the release of first reactions and initial waves of reviews.

RELATED: Russo Brothers (and Thanos) Ask Fans Not to Spoil Infinity War

Even $200 million may be a little timid, considering Black Panther shattered records in February with a $202 million haul in its opening weekend (the film has grossed nearly $1.3 billion to date). Considering Infinity War features virtually every hero in the Marvel Cinematic Universe and serves as the culmination of a storyline that begin in 2012 with the introduction of Thanos in the mid-credits scene of The Avengers, theaters will no doubt be packed on April 27.

That said, Deadline points out that April releases typically hit a U.S. box-office ceiling in the low to mid-$100 million range, with Furious 7 opening to $147 million, Fate of the Furious to $98.7 million and The Jungle Book to $103.2 million. However, if any film can test those limitations, it's likely Infinity War.

RELATED: Marvel's Superheroes Reveal Avengers: Infinity War Character Posters

Directed by Joe and Anthony Russo, Avengers: Infinity War stars Robert Downey Jr., Chris Evans, Chris Hemsworth, Mark Ruffalo, Jeremy Renner, Scarlett Johansson, Paul Bettany, Anthony Mackie, Paul Rudd, Elizabeth Olsen, Tom Holland, Benedict Cumberbatch, Chadwick Boseman, Chris Pratt, Zoe Saldana, Dave Bautista, Bradley Cooper, Vin Diesel, Tom Hiddleston and Josh Brolin, among others.