"Captain America: Civil War" will feature the introduction of Spider-Man into the Marvel Cinematic Universe, following two previous feature film franchises (and five feature films) produced by Sony Pictures. A deal struck last year between Marvel Studios and Sony allows the wall-crawler to play a part in Marvel's shared universe, and he'll also get an all-new solo film in 2017 set in his new cinematic home.
The title of that film, which will star Tom Holland and Zendaya, has not yet been revealed, but a new domain registration might just offer new information about that title. A domain for title "Spider-Man Homecoming" has been registered by Sony; information about the domain reveals that Sony registered it at the start of the month. Additionally, visiting spidermanhomecomingthemovie.com redirects to Sony's website. Sony has not yet confirmed that "Homecoming" is the title or part of the film's title.
"Amazing Spider-Man" #252, the issue from 1984 wherein Peter Parker returns from the "Secret Wars" crossover with a new black costume, also had the title "Homecoming." It's unlikely that this has any connection to the film, however, as Marvel has notably used comic book titles for films unrelated to the comics (like "Avengers: Age of Ultron"). It's more likely that if this is indeed the title of the "Spider-Man" film, it's referencing the character's integration into the Marvel Cinematic Universe following two previous film franchises produced in separate continuities solely by Sony.
Spider-Man debuts in "Captain America: Civil War" on May 6; the solo "Spider-Man" feature film arrives in theaters on July 7, 2017.