Grey's Anatomy is the longest-running medical drama and one of the longest-running series in television. The show, whose title is a reference to the mid-1800s anatomy textbook, premiered on ABC in 2005. Grey's Anatomy is currently on its 18th season, and was already renewed for a 19th season.
The cast contains 13 members, only three of which are from the original cast. Since its premiere, a few spin-off series have been created, like Private Practice and the current series Station 19. Also since its premiere, Grey's Anatomy has featured some of the most unbelievable plot points that only ruined the show.
10 Izzie Abruptly Leaving After The Merger
While rumors have spread that Katherine Heigl's sudden departure from Grey's Anatomy is because she's difficult to get along with, Heigl denies this and declares it was due to her becoming a first-time mother. After the show reveals Izzie has terminal brain cancer, she quickly marries Alex Karev.
Meredith and Derek gift Alex and Izzie their huge wedding due to Izzie's terminal diagnosis. Miraculously, Izzie survives and beats cancer, but not without Richard Webber firing her shortly after her return to work during the early stages of the Seattle Grace, Mercy West merger. As a result, she irrationally blames Alex when she learned he voiced concerns about her health. She leaves him by leaving him a note at work. She makes a brief return a few episodes later, only to take off again when Alex refused to reconcile.
9 The Creepiness Of Denny's Return As A Ghost
The storyline between Izzie and her fiancé Denny Duquette is one of the worst storylines in Grey's Anatomy history. Izzie falls for her patient Denny as he is waiting for a heart transplant. To ensure Denny gets a new heart quickly, Izzie cuts his L-VAD wire. Denny proposes to Izzie and receives a heart transplant. However, he suddenly dies from a stroke before they even go on their first date. Denny appears as a ghost later on when Izzie and Alex are in a relationship and the two of them creepily reunite. In more ways than one. It turns out Izzie was hallucinating Denny. It was one of the symptoms she had due to the cancer that spread to her brain. Though this reunion was meant as fan service, it ended up being a pointless and strange reunion that no one asked for.
8 The Jane Doe Falls In Love With Alex
Why do all the crazy storylines involve either Alex, Izzie, or both? Alex encounters a pregnant woman crushed by a cement pylon, who he rushes to the hospital. When the woman wakes up, she is classified as a Jane Doe because she doesn't remember her name or anything about her life. She eventually chooses the name Ava. Ava bonds with Alex, and the two of them fall in love. However, when Ava's memory returns fans learn her real name is Rebecca, and her husband arrives to take her home. She reluctantly leaves with him to Alex's disappointment. Later on in the series, Rebecca returns to be with Alex. She unfortunately has a hysterically pregnancy, and mental breakdown that causes her to attempt suicide.
7 Derek And Rose's Brief Back-And-Forth Relationship
The brief relationship between Derek and his nurse Rose, who worked on 36 surgeries with him before the pair ever made eye contact, was just a waste of time. Derek and Rose only go on a few dates, but Derek is obviously still interested in Meredith throughout the entirety of their relationship. Derek kisses Meredith after saving their first clinical trial patient, and has to break up with Rose. Rose takes the break-up well at first, but later pretends she is pregnant and is furious with Derek for leading her on.
6 The Random Appearance Of Mark Sloan's Daughter
While fans are familiar with Derek aka McDreamy, they can't forget Mark Sloan aka McSteamy. Mark, who is the shows biggest player, finds out he has a daughter. Fans weren't really surprised. Her name is Sloan Riley. Seriously.
Sloan discovers Mark is her biological father and runs to him when her mother kicks her out for being 18 and pregnant. After many pregnancy complications, Sloan gives her baby to a couple from Washington, knowing Mark desperately wanted to raise the baby. Sloan is one of the more unlikable guest characters from Grey's for her ditsy mindset and rude tendencies.
5 The Weird Fling With George And Meredith
While Meredith and Derek are by the far the most well-known couple in Grey's Anatomy, Meredith also has a weird fling with her roommate, George. After Derek gets back together with Addison, and Meredith confronts her father after 25 years, she is overwhelmingly sad. George notices this and confesses his love for her. Meredith and George sleep together, but both realize it was a bad decision and regret it immediately. The pair slowly build back their friendship after that uncomfortable night, but George tragically dies later in the series.
4 Miranda Bailey's OCD Diagnosis Isn't Mentioned Again
Miranda Bailey is one of the original cast members of Grey's Anatomy and has appeared in almost 400 episodes. Her strict personality is introduced to viewers when the interns arrive at the hospital during the first season. She's on of the best surgeons Grey Sloan has ever seen and later becomes Chief of Surgery.
During the ninth season, an investigation takes place after three of her patients die from an infection. Bailey starts to exhibit strange behaviors, like over-washing her hands, and pulling her fingers. She is soon diagnosed with OCD. Grey's Anatomy doesn't touch on this plot point much else after the episode airs.
3 Alex Going To Kansas To Get Back Together With Izzie
Yet another Alex Karev plot point that just doesn't make any sense. Justin Chambers, who spent 16 years as a Grey's Anatomy cast member, abruptly leaves the show to diversify his acting roles.“There’s no good time to say goodbye to a show and character that’s defined so much of my life for the past 15 years,” Chambers said in a January statement. “For some time now, however, I have hoped to diversify my acting roles and career choices," said Chambers in an interview with Hollywood Reporter.
Alex leaves his current wife Jo, and decides to return to his former flame Izzie, in Kansas. Viewers learn Izzie used frozen embryos and currently has 5-year-old twins with Alex. This departure came out of nowhere as Alex was very happy with Jo and was adamant about starting a life with her.
2 Jackson and Maggie's Relationship As Step-Siblings
Maggie Pierce is the biological daughter of Ellis Grey and Richard Webber, making her Meredith's half-sister, but the pair butt heads at first. Maggie serves as the co-head of Cardiothoracic Surgery at Grey Sloan Memorial Hospital. After her adoptive mother's tragic death, Jackson comforts Maggie, which leads to a relationship.
Although, Jackson is best recognized for his relationship with April. What's even weirder is Maggie's biological father Richard, is married to Jackson's biological mother Katherine, making the couple step-siblings. That's hard to ignore.
1 Exactly What Is The Grey's Anatomy Musical Episode?
Grey's Anatomy fans have different opinions about the musical episode. After Callie, goes through her windshield in a car accident, she suddenly starts... singing? The episode, which is titled Song Beneath the Song, features various cast members bursting out into song during serious plot points. The episode, which celebrated its 10th anniversary last year, includes covers of songs like The Fray's "How To Save a Life" and Snow Patrol's "Chasing Cars." It's almost as bad as Riverdale's musical episode. Almost.