Beginning life in the 60s, Marvel's Fantastic Four comics have engrossed audiences of all ages, offering a light and fun sci-fi adventure. Marvel's First Family has fought many challenging adversaries, with Doctor Doom standing as their greatest villain. With the MCU poised to adapt the Fantastic Four for the big screen, fans are sharing their favorite comics featuring the team encountering Doom.

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The Fantastic Four have engaged in several intense battles with Doctor Doom, providing some of Marvel Comics' most gripping storylines. The Fantastic Four's fights against Doctor Doom provide some real stand-out moments in superhero comics.

10 "The Return Of Doctor Doom"

Doctor Doom returns to battle the Fantastic Four

Doctor Doom has become a major hit among fans, who delight in witnessing his villainous ways. The scheming antagonist's return came fairly quickly after his Fantastic Four debut. "The Return of Doctor Doom" sees Reed Richards and Victor Von Doom swap bodies, in a lighthearted tale from Stan Lee.

This wonderfully daft Fantastic Four comic generates plenty of laughs, as Doctor Doom tricks the Fantastic Four into believing he is Reed Richards. The comic strip possesses an excellent sense of humor, with Reed desperately trying to convince his teammates that he's not Victor, while his dangerous rival Doctor Doom tarnishes Mister Fantastic's heroic image by undertaking his evil plans.

9 "The Origins Of Doctor Doom"

Doctor Doom sits on his throne in Latveria

Considered one of Marvel's most popular villains, Doctor Doom has posed a major threat to the Marvel Universe, ever since his early 60s beginnings. Fantastic Four's comics later revealed his origin story, in "The Origins of Doctor Doom," which offers readers a fascinating glimpse at Victor's early beginnings

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This truly enthralling story brings a new perspective on the Fantastic Four's Doctor Doom, as audiences are shown how he became Latveria's fearsome ruler. "The Origins Of Doctor Doom" brings some added depth to the Marvel villain, with viewers witnessing the start of his rivalry with Mister Fantastic, and learning how Doctor Doom's face became disfigured, making this an essential read for Fantastic Four fans.

8 "Terror In A Tiny Town"

Doctor Doom leers over a tiny town.

Superheroes living alternate lives has often proved an appealing concept, with comics readers hooked by this heightened concept. Fantastic Four's take on this narrative style is no different, with the comic book storyline "Terror in a Tiny Town" transporting the Fantastic Four into a suburban lifestyle.

Marvel's First Family is given a unique twist in this Marvel storyline, as they live perfectly ordinary lives while being tormented by dreams of their "real" vigilante battles. This curious plot point is later revealed to be the work of Doctor Doom and the Puppet Master, providing an exciting team-up for two of Fantastic Four's most compelling bad guys.

7 "Prisoners Of Doctor Doom"

Doctor Doom gloats about luring the Fantastic Four into his trap.

The Fantastic Four biggest standout of their devious adversaries is arguably Doctor Doom, who makes his debut in "Prisoners of Doctor Doom." This quirky tale follows Doom as he enlists the Fantastic Four in locating Blackbeard's treasure, embracing the irreverent tone that Marvel has become known for.

"Prisoners of Doctor Doom" does an amazing job at establishing one of Marvel Comics' most destructive rivalries. The story expertly establishes the personal history between Reed and Victor, revealing the pair to be old schoolmates, who drifted apart after Victor was expelled following a failed school experiment. With Victor blaming Reed for his expulsion, "Prisoners of Doctor Doom" establishes Doom as one of Marvel's best villains.

6 "Comes The Hunger"

Doctor Doom captures and tortures the Thing

The Fantastic Four can often prove a flawed family unit, and "Comes the Hunger" is the perfect demonstration of some of their less desirable personality traits. "Comes the Hunger" is a powerful Fantastic Four storyline, which sees the Thing furiously confront Doctor Doom over Sharon Ventura's apparent demise.

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This deeply emotional Fantastic Four plot sees Ben Grimm making one of his biggest mistakes, as he seeks revenge against Doom. Wrongly believing Sharon to have been killed by their arch nemesis, the Thing's impulsive nature leads to him becoming Doom's prisoner. The story also brilliantly shows the Fantastic Four at their most vulnerable, suffering from some serious injuries after their latest battle, showing a more vulnerable side to the team.

5 "Solve Everything"

The Fantastic Four's Reed Richards exacts his plan in his lab to solve all problems across every universe.

Although Reed Richards may appear the least interesting Fantastic Four member, in reality, he is one of Marvel's most complex protagonists; a Marvel hero with an incredibly loose honor code. Doctor Doom's presence in "Solve Everything" magnificently demonstrates Reed's darker side, as the Fantastic Four's leader witnesses the Council of Reed's cruel treatment of their mortal enemy.

"Solve Everything" is a profound Fantastic Four story, with Reed attempting to solve all the universe's problems. Reed's reclusive nature is his greatest weakness, as he isolates himself from his friends and family in pursuit of his mission. The narrative also reveals the Council of Reed's immoral actions, which sees them brutally murdering several Doctor Doom variants, representing Reed's ghastly potential.

4 "The Battle Of The Baxter Building"

Doctor Doom stands on top of the Baxter Building with a weapon, while three of the Fantastic Four (Sue Storm, Johnny Storm and The Thing) try to stop him.

The Fantastic Four's headquarters is one of the most famous aspects of the comics, serving as an ever-reliable base of operations for the superheroes. "The Battle of The Baxter Building" features Doctor Doom taking over their homestead, in an action-packed Marvel Comics venture.

Featuring a Fantastic Four without their powers, "The Battle of The Baxter Building" provides a fantastic underdog story. With Doctor Doom appearing to have the upper hand, the storyline sees the four heroes truly rise to the occasion, and prove that they don't need their powers to save the day. The usually warm and welcoming Baxter Building is turned into a deadly and intimidating environment for the Fantastic Four, as Doom takes over the headquarters' defense systems.

3 "The Micro-World Of Doctor Doom"

Doctor Doom holds the Fantastic Four in his hand, while Ant-Man is glimpsed through a magnifying glass.

Team-up events have become one of the most popular stories in the comic-book medium, and one of the earliest examples is the Fantastic Four comic "The Micro-World of Doctor Doom." This fun comic escapade involves the Fantastic Four joining forces with Ant-Man - who has delivered some of Marvel Comics' best quotes - after they are shrunken in size by Doctor Doom.

This charming Fantastic Four story gives readers a comedic venture, with Marvel's First Family dealing with the terrifying threat of an air vent while in microscopic form. The story also introduces the tiny Sub-Atomica world, which delivers some gorgeous visuals. Meanwhile, Doctor Doom poses a powerful presence throughout the comics, as he holds the Fantastic Four and Ant-Man prisoner.

2 "Enter... Doctor Doom!"

The Fantastic Four fly around an enlarged Doctor Doom

The Fantastic Four are among Marvel's most capable vigilantes, with their strength and expertise allowing them to triumph against some of the universe's greatest threats. "Enter... Doctor Doom!" turns the tables magnificently on their winning streak, with a plotline that shows Doctor Doom acquiring the Silver Surfer's power.

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Presenting Doctor Doom as a truly unstoppable threat, this Fantastic Four comic delivers a grim and doom-laden story. Usually reliant and dependable, here the Fantastic Four finally meet their match, as a Doctor Doom powered by the Power Cosmic overwhelms them. It's a tense, nail-biting comic, which places Marvel's First Family in an impossible situation.

1 "I Want To Die"

Fantastic Four's the Thing grabs the Throb away from Sharon

Although Doctor Doom has developed a reputation as one of the Fantastic Four's most evil foes, he has still occasionally shown a less sinister side. A case-in-point is the Marvel Comics story "I Want To Die," which sees Doom console a suicidal Sharon Ventura, following her mutation into a monstrous creature.

Fantastic Four's deep and emotional plot superbly humanizes Doctor Doom, as he comforts the troubled young woman. "I Want To Die" reveals a more caring side to Doom, as he offers to help Sharon find a cure for her mutation. Additionally, it demonstrates the Fantastic Four's prejudices against their arch-enemy, wrongly assuming the worst in Doctor Doom and refusing to accept that he is capable of kindness.

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