One of the most powerful artifacts in the Marvel universe is the Infinity Gauntlet. It holds the six Infinity Gems that enable its wielder to control reality. The Infinity Gems need to be in the perfect place to optimize the Gauntlet to its maximum potential. It's not rocket science to guess that whosoever wields the Infinity Gauntlet wields omnipotent power. In the Infinity Gauntlet (1991) #1, the Mad Titan Thanos seized it. Not only did he prove himself worthy of Death's affection, but he also became unstoppable, an all-powerful God.
Avengers: Endgame gave us a peek into two characters who wore the Infinity Gauntlet. But as one reads through Marvel's history, many characters have worn it over time.
10 TONY STARK
Let's start off with the godfather of Marvel Universe, Tony Stark aka The Iron Man. In the heroic age, he becomes the first human to wield the Infinity Gauntlet. This pertains to the return to a story from Avengers Vol. 4. The post-Dark Reign period brought with itself many things of the past, of which the Infinity Gauntlet was one.
While in prison, Parker Robins aka The Hood discovers the location of one the Infinity Gems that belonged to Black Bolt of the Inhumans. In this timeline, Black Bolt was dead and his subjects were unaware of the gem. Although Parker Robins succeeded in gaining access to Infinity Gem, the next part of his plan is thwarted by Iron Man and The Hood was sent back to prison (after briefly wearing the Gauntlet). Tony completed the gauntlet before giving each of the gems to members of the Illuminati to keep them safe.
9 ADAM WARLOCK
This story comes from Infinity Gauntlet #6 (1991), wherein Nebula and Adam Warlock battle it out for the Infinity Gauntlet. Adam Warlock transfers himself into the Soul Gem and thwarts Nebula's control over the rest of the Gems. Adam takes the Gauntlet from Nebula, if only for a short period of time. The Living Tribunal of Celestials decides to intervene and force Warlock to disperse the gems.
8 SPIDER-MAN
This story features in Avengers and the Infinity Gauntlet (2010) as a marked effort by Marvel to retell stories in a humorous way. Turns out, Thanos has all of the Infinity Gems so he does what he's best at, wiping out heroes.
A bunch of superheroes unite under the leadership of Spider-Man. In a comical way, Peter steals the Gauntlet off of Thanos' hand. He uses the Gauntlet to rewrite the timeline and bring back the dead superheroes again.
7 REED RICHARDS
Known as Mr. Fantastic, Reed Richards became one of the Superheroes to wield the Infinity Gauntlet. Not only did MCU bless him with exceptional intelligence, but also with the opportunity to wield the Gauntlet.
This story pertains to New Avengers: Illuminati #2 wherein despite building the Gauntlet, Reed wanted to be done with it once and for all. As Reed wears the Gauntlet and wills the gem out of existence, he is prevented by doing so due to the temptation of its power.
Eventually, Reed decides to give each of the Infinity Stones to members of the Illuminati in order to keep them safe. It also calmed Reed's fears of seeing the Earth destroyed by the power of the Infinity Gauntlet.
6 ULTIMATE HULK
In the Ultimate Comics: Ultimates #25 (2011), the Gauntlet bore eight Infinity Gems, instead of six. The story pertains to the ambush of S.H.I.E.L.D by Kang the Conquerer. Hulk who was imprisoned there was let free. Imagine a locked up Hulk suddenly let loose with an Infinity Gauntlet nearby. Although Hulk wore the Gauntlet, not all the gems were present. Before all was over, the Ultimates managed to defeat the Hulk.
Had these two scenarios not worked out in The Ultimates, imagine what Hulk's pent-up frustration could have done.
5 LOCKJAW
In Lockjaw and the Pet Avengers #4, Lockjaw and Pet-Avengers set on an outer-space quest to gather the Infinity Stones. It won't be out of place to mention that Lockjaw in the past, has been an escort to the Royal Family and a teleporter to the Inhumans.
Because Lockjaw serves the Inhumans, he discovers the mind gem buried near their home, Attilan. Coincidentally, Reed Richards happens to be looking for Infinity Stones too. The telepathic dog scans Reed's mind and decides to grab the Gauntlet for himself. Except for a brief ambush by Thanos, Lockjaw assembles all the Gems and makes an Infinity dog-collar out of it.
By the end, Lockjaw and his furry friends present the Gauntlet to a startled Reed Richards.
4 CAPTAIN AMERICA
This story pertains to New Avengers #3 (2013) wherein Captain America serves in the Illuminati. As per Black Panther's discovery, another Earth dangerously hangs over Wakanda. Upon further investigation, this phenomenon is reported to be a part of a multi-versal chain reaction. This could potentially destroy universes.
So Captain America unsuccessfully wields the Infinity Gauntlet to stop the impending danger. An unfinished attempt by Captain America leaves the Illuminati no other choice but to destroy the Earth colliding into theirs.
3 BLACK PANTHER
This is a direct continuation from the previous entry wherein the Earth's have collided into one another. Before this apocalypse, however, Strange makes a startling discovery. It is revealed that Doctor Doom possessed Beyonders powers that made him into a mighty god, ruling over Battleworld. And he's responsible for the collision.
This story pertains to Secret Wars #6-9 (2015), wherein Black Panther and Namor discover the Infinity Gauntlet on Stephen Strange's island. Black Panther wields the gauntlet to defeat Doom. All is well after Doom is toppled and Black Panther transports back in time to alter reality.
2 DEADPOOL
This comical story comes from Deadpool #45 (2015) wherein Deadpool is placed into Infinity Gauntlet mini-series. Thanos hires Deadpool to steal the Infinity Gauntlet, but Deadpool pulls a switcheroo on him. He keeps the original for himself and gives Thanos a replica.
Deadpool uses the Gauntlet to roast his every enemy. Starting with Thanos, moving on to everyone else in the Marvel Universe. Soon he realizes the futility of his actions. In the typical Deadpool fashion, he ends the roast by breaking in the fourth wall and slamming his readers. Deadpool resets the whole thing and returns the Gauntlet to Thanos.
1 SANTA CLAUS
In Marvel Holiday Spectacular (2009), Iron Man summons the Illuminati to help Santa. Turns out Santa's reindeer are Skrulls. So Santa is left without his most important aid on holidays. The Illuminati let Santa borrow the Infinity Gauntlet to deliver gifts to people. Once Santa wields the Gauntlet, he goes bonkers with power. He's only stopped when Namor throws a snowball and knocks the Gauntlet off his hand. Iron Man then fixes Santa up with a robot reindeer to deliver gifts. Oh, the hilarity!