DC Entertainment President Diane Nelson will step down from her position and leave Warner Bros., as reported by THR on Wednesday. Nelson held the job of DC Entertainment President since 2009, and had been with Warner Bros. for more than 22 years.

"Warner Bros. has been my home for over 20 years with a wide variety of incredible professional experiences," Nelson said in a statement, quoted by The Hollywood Reporter. “The last nine — rebuilding and managing DC Entertainment -- have been a particular highlight and privilege."

RELATED: DC President Diane Nelson to Take Leave of Absence, Plans Return

In March, it was announced that Nelson was taking a leave of absence from Warner Bros. in order to spend time focusing on family, but planned to return to the company. It's reported by THR that Nelson "very recently" decided not to return from her leave.

"Diane has been a friend and colleague as well as a valued member of the Warner Bros. family for more than 20 years,” Warner Bros. Entertainment CEO Kevin Tsujihara in a statement. "Throughout her tenure, her leadership and contributions have helped shape the way the studio operates today, and we’re better for having had her on our team. While we’re sad she’ll be leaving us, we completely respect and support her decision."

Nelson, who also held the position of President of Warner Bros. Consumer Products, has been with Warner Bros. since 1996, when she joined in the role of Director of Worldwide Corporate Promotions. In her time with the company, she’s also served as President & Chief Content Officer of Warner Bros. Interactive Entertainment and President of Warner Premiere, and worked closely with managing the multimedia Harry Potter property.

THR notes that, in the interim, Thomas Gewecke, Warner Bros.’ Chief Digital Officer and EVP, Strategy and Business Development, will continue to oversee DC executives including Publishers Dan DiDio and Jim Lee, DC Entertainment President and Chief Creative Officer Geoff Johns and Executive Vice President Amit Desai, as he has during Nelson's leave of absence.

In Nelson's time as DC President, the company has launched bold publishing initiatives including The New 52, DC You and DC Rebirth. In 2015, DC publishing moved from its birthplace of New York City to Burbank, California, joining the rest of the company on the west coast. DC has seen major talent acquisitions in recent years, including longtime Marvel creators Brian Michael Bendis and John Romita Jr.

Under Nelson, DC has also seen a greatly increased presence in both television and film. While DC's recent film efforts have a mixed record of both critical and box office success, Nelson has been known to be a champion of Wonder Woman specifically -- naming Princess Diana of Themyscira as her favorite character. She was a visible proponent of the 2017 hit film, and in 2014 told shareholders that she "very conscious" of the need for greater female representation at DC, both in the characters featured and the creators bringing the stories to life.

DC's television success has been notable, adopting the shared universe model that has brought both DC and Marvel success in comic books for years (and Marvel on the big screen) to network TV with The CW's Arrow, The Flash, Supergirl and DC's Legends of Tomorrow; along with non-Arrowverse standouts including Gotham, Black Lightning and iZombie.

Keep reading CBR for any updates on Nelson's next moves, and what this shift means for DC's corporate structure.