Here's #36! Click here for the master list!
Amazing Spider-Man (Vol. 2) #36
This is one of the tricky ones on the list, as there are very likely more important comic issues, in the sense that important things happened in other books.
To wit, The Brave and the Bold #36 gave us the first Shadow Thief, Fantastic Four #36 was the first appearance of the Frightful Four (as well as the first appearance of Medusa) and finally, perhaps most notably, Hugo Strange debuted in Detective Comics #36.
However, I don't think any of them are as memorable of an issue as Amazing Spider-Man #36, which was the 9/11 tribute issue by J. Michael Straczynski, John Romita Jr. and Scott Hanna.
Not everyone likes this story (I know quite a few people who absolutely hate it), but everyone can concede that this issue was NOTABLE, at least.
Whether you agree with me that it is the MOST notable 36th issue, well, that's a separate matter!
Anyhow, that's the pick! Any other good #36s that should get an honorable mention? Perhaps an issue of Sandman or Swamp Thing or Doom Patrol?