WARNING: The following contains spoilers for The Immortal She-Hulk #1 by Al Ewing, Jon Davis-Hunt, Marcio Menyz, and VC's Cory Petit, on sale now.
Tony Stark is a superhero, but he's also human which means he can make mistakes and errors in judgment. Unfortunately for Jennifer Walters, aka She-Hulk, Stark's errors have cost her her life on more than one occasion. In The Immortal She-Hulk #1, Walters remembers these deaths and hints that she holds Iron Man at least partially responsible.
Stark and Walters have a long history. Often at odds with each other, but also friends at times, they're the very definition of "it's complicated." In The Immortal She-Hulk #1, She-Hulk remembers the times she died and waxes philosophical about them. The common thread among more than one of them seems to be Tony Stark. Stark has a genius-level intelligence and undeniable strength in his beliefs, which is part of what makes him a hero. But he is also stubborn and often believes that he alone knows what's best for the rest of the world.
Jenn isn't the only Hulk that Stark has wronged in the past. Just take the time he launched her cousin, the Hulk, into outer space. Granted, Stark didn't make this decision alone, but the bulk of the blame does rest squarely on his shoulders. What makes this decision even worse is Stark's treatment of She-Hulk. Prior to the events in World War Hulk, by Greg Pak, John Romita Jr., Klaus Janson, and Christina Strain, Stark injects She-Hulk with SPIN nanites and deactivates her powers. Stark was concerned about She-Hulk's reaction to him shooting the Hulk into space, so he de-powered her. Stark restores her powers during the storyline but then takes them away again immediately after.
As She-Hulk ponders two of her deaths in The Immortal She-Hulk #1, she remembers that one of them took place during Civil War II, by Brian Michael Bendis, David Marquez, Clayton Cowles, and Justin Ponsor. During this event, the Inhuman Ulysses, a precog with the ability to forecast potential crimes and act to stop them before they happen, something that Captain Marvel wants to do. Danvers used this power in some questionable ways sparking the disdain of Iron Man, who was against predictive policing. One of the events foreseen was Thanos arriving on Earth "to steal a Cosmic Cube and kill the world with it."
Captain Marvel led the battle against Thanos, but both War Machine and She-Hulk were casualties in the attack. On Jennifer's deathbed, Stark argued with and blamed Captain Marvel for the two deaths. But according to She-Hulk, Stark was most upset about not having been consulted about the threat from Thanos. "We'd lost so much to save so many lives," She-Hulk says, "and [Stark] didn't care." As Jennifer took her last breath, she cursed Tony Stark. "You could say Tony Stark's need to always be right got me killed." It seems Stark's ego is so huge that saving the world takes second place to it.
The other death that She-Hulk blames on Tony Stark occurs during the Empyre event series, by Al Ewing, Dan Slott, Valerio Schiti, and Marte Gracia. In Empyre, the plant-like aliens, the Cotati, ask the Avengers for help in fighting the Kree/Skrull alliance. The Cotati, however, is using the Avengers to help defeat the armada so they can move forward in their plans to invade Earth. Early in the series, Swordsman took She-Hulk aside in order to give her a weapon that would help her fight against the Kree and the Skrulls, but The Cotati knew how powerful She-Hulk is and separated her from the others and is killed. "They split me off from the others. Trusting as a lamb... Then they were tearing into my brain." The Cotati are able to possess dead bodies and killed She-Hulk and used her as a puppet in order to infiltrate the Avengers. She-Hulk blames Tony Stark for this death because it was Iron Man who insisted the Cotati were friendly and didn't have ulterior motives. She died because once again, "Tony always had to be right."
With She-Hulk getting her own streaming series, it will be interesting to see if any of these story elements make it to the small screen, depending on what direction the show goes with. Stark's legacy in the MCU is firmly established and it will be interesting to see if writers will tarnish Tony's character post-mortem. Iron Man will always be a hero, but as She-Hulk points out, Iron Man is not the flawless genius everyone thinks he is.