Move over, Peter Parker -- S.H.I.E.L.D.'s Leo Fitz and Jemma Simmons are headed to Disney XD's "Ultimate Spider-Man vs. The Sinister 6." In a new clip from "Lizards," "Agents of S.H.I.E.L.D." stars Iain De Caestecker and Elizabeth Henstridge get animated in order to guest on the show. Spidey and Iron Spider will encounter the dynamic duo as they attempt to uncover Doc Ock's mole inside S.H.I.E.L.D. Academy.

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According to Variety's description of the episode,

Due to Vulture's revelation that Doc Ock has a spy inside the SHIELD Academy, the Web Warriors decide to search for the mole. When they confront Dr. Curt Connors, he seemingly turns himself into The Lizard and attacks SHIELD with a venomous bite that spreads like a virus, also turning its victims into lizards.

Starring Drake Bell as Spider-Man, "Ultimate Spider-Man vs. The Sinister Six" airs Sundays at 9 a.m. on Disney XD.