June 22 is undoubtedly a bittersweet date for fans of True Blood, as it not only marks the return of the series but also the beginning of the end, because the seventh season will be the last for the HBO supernatural drama. And judging from this new trailer, which debuts the first footage from Season 7, the residents of Bon Temps are going out with a bang: sick vampires, religious zealots and an uncaring government.

True Blood returns Sunday, June 22 at 9 p.m. ET/PT on HBO.