The first TV spot for Fox's The Gifted depicts a different world, one where mutants are feared, hated and, yes, hunted. It's a world familiar to readers of Marvel's X-Men comics, hammering the themes that have fueled the franchise for more than five decades.

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The new series, which unveiled a full-length trailer two weeks ago, follows a family whose life is turned upside down when they learn their teenage children possess extraordinary abilities. Forced to go on the run from a hostile government, they turn to an underground network of mutants for help and must fight to survive.

However, as we learned in that first look, the Struckers aren't an "ordinary" family. Potential ties to Marvel Comics history aside, the father, Reed Strucker (Stephen Moyer of True Blood), works for a U.S. government agency tasked with identifying and apprehending mutants, which certainly adds another layer of drama to a situation already fraught with tension.

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This promo of course zeroes in on the dangers facing mutants, showcasing footage of young Andy Strucker being bullied at school, Lorna Dane/Polaris unleashing her powers on police, and everyone fleeing from the new spider-like Sentinels.

Airing Mondays at 9 p.m. ET/PT this fall on Fox, The Gifted also stars Amy Acker as Caitlin Strucker, Sean Teale as Marcos Diaz/Eclipse, Coby Bell as Jace Turner, Emma Dumont cast as Lorna Dane/Polaris, Jamie Chung as Blink/Clarice Fong and Blair Redford as John Proudstar/Thunderbird, Natalie Alyn Lind as Lauren Strukcer and Percy Hynes White as Andy Strucker.