The end is nigh for "The 100." A series of nuclear power plants have begun to melt down, which means that 96% of the Earth's surface will soon become uninhabitable -- and that spells doom for Clarke and her crew in the first trailer for Season 4.

This first look into "The 100" Season 4 reveals several of the trials and tribulations that the survivors will face as the Earth goes nuclear. For one, there will be "the black rain," which will contaminate all of the drinkable water. Then comes the radioactivity and the cancer that follows -- and that's only if they don't kill each other first.

Starring Eliza Taylor, Bob Morley, Marie Avgeropoulos, Isaiah Washington, Henry Ian Cusick and more, "The 100" returns to The CW on Wednesday, February 1.