Doctor Strange director Scott Derrickson today teased the return of the good doctor’s mystical headquarters, the Sanctum Sanctorum, in the upcoming film Avengers: Infinity War. Derrickson confirmed the location will play some role in Infinity War when he uploaded an on-set picture featuring the film’s directors, Anthony Russo and Joe Russo, standing in the Sanctum Sanctorum.

The Sanctum Sanctorum is the magical headquarters of Doctor Strange, the Sorcerer Supreme, that was first introduced in Strange Tales #110 in 1963. The building’s look and history was updated for its big screen debut in the 2016 film Doctor Strange, becoming just one of three protective sanctums located around the world, the trio of which formed a protective barrier around the Earth meant to ward off powerful, otherworldly magic.

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There’s no telling exactly what role the Sanctum Sanctorum will play in Infinity War, but one of the three protective sanctums was destroyed in Doctor Strange. With the alien conqueror Thanos likely to play a major role in Infinity War, it’s reasonable to speculate that any threats the Mad Titan might send to Earth would have a significantly easier time making landfall now that the mystic barrier has partially fallen.

Avengers: Infinity War is a production of Marvel Studios directed by Anthony Russo and Joe Russo starring Robert Downey Jr., Josh Brolin, Mark Ruffalo, Tom Hiddleston, Chris Evans, Chris Hemsworth, Jeremy Renner, Chris Pratt, Elizabeth Olsen, Sebastian Stan, Benedict Cumberbatch, Paul Bettany, Samuel L. Jackson, Cobie Smulders, Benedict Wong, Zoe Saldana, Karen Gillan, Vin Diesel, Dave Bautista, Pom Klementieff, Scarlett Johansson, Benicio del Toro, Tom Holland, Anthony Mackie, Chadwick Boseman and Danai Gurira.

(via SuperHeroHype)