Marvel's "Agents of S.H.I.E.L.D." ended its third season with a number of shakeups to the cast and characters. Lincoln and Hive/War died, Daisy went rogue (and went shopping at Hot Topic), and Coulson lost his status as Director of S.H.I.E.L.D. Fans also lost Bobbi and Lance, who exited to star in a spinoff series that was not picked up to series.

After Comic-Con International, we learned of just a few of the changes ahead in Season 4. The Robbie Reyes version of Ghost Rider is being thrown into the mix along with a brand new Director of S.H.I.E.L.D. played by Jason O'Mara.

RELATED: "Agents of SHIELD": Why Ghost Rider Will - or Won't - Be Marvel TV's Savior

If Ghost Rider's inclusion had you shaking your head and saying, "Wait, what?!", you're not alone. For a show that's been almost entirely grounded in science and genetics through its first three seasons, the mystical side of the Spirit of Vengeance seems a bit out of place. But showrunnersJed Whedon and Maurissa Tancharoen said they plan to blend science and magic in the upcoming season. With Ghost Rider bringing a whole new -- and wholly unexpected -- element to the series, we look at a dozen other characters from the Marvel Comics Universe that could do the same for Marvel's "Agents of SHIELD."

12 Moondragon



HeatherDouglas, AKA Moondragon, is a telepath, martial arts master and geneticist with a somewhat convoluted origin story. When she was a child in Los Angeles, her family came upon Thanos landing his spaceship -- so, like any villain, he blew up her family's car and left her as the lone survivor; her father's being (or something) was then transferred into Drax the Destroyer. While the MCU might not be able to make her Drax's daughter (or fit that entire backstory into their 'verse), she'd be a great addition considering she's also been an Avenger and a member of the Guardians of the Galaxy, which would help strengthen ties between Marvel Studios' film and TV properties. Moondragon is also openly bisexual. She'd be a much needed badass LGBTQ character added into the MCU and someone that could expand their space-related world on Earth, even if she never makes it into the cosmos, and vice versa.

11 Daimon Hellstrom



Having Ghost Rider appear in the upcoming season really opens the door for other mystical Marvel comics characters. Hellstrom first appeared in "Ghost Rider" and is the literal son of Satan (which was later retconned as him being the son of a demon who took the form of Satan... not that the TV side couldn't streamline his origin). While the show might not be ready to have the actual devil appear on screen, Ghost Rider's arrival means the show is definitely ready for demons and monsters. Hellstrom and his ham-fistedly-named sister, Satana, have been around the Marvel Universe for quite some time now and could make for a great story arc on the ABC show. Hellstrom being the sibling raised by his human mother and Satana the one raised by their demon father. Hellstrom himself also changes sides often and has been an ally to Doctor Strange on more than one occasion (most recently helping Strange in "Civil War II"). With "Doctor Strange" arriving in theaters this November, he would provide yet another way to expand the TV world and connect it with the films.

10 Noh-Varr



Noh-Varr, AKA Marvel Boy, AKA Protector, has had a weird history. He's been both an Avenger and member of the Young Avengers. He loves showing off his abs (like, a lot) and is pretty damn charming. He also enjoys the band The Ronettes. As a member of the alien race known as the Kree, which has already been established in the MCU (and bonus points for him not being a blue Kree, which means he'd look less silly on screen), his inclusion would go a long way to having the race be more than just a magical plot device when needed. His version of the Kree is actually from an alternate dimension -- he only came to this dimension when his ship was shot down while cruising through the Marvel Universe we know and love -- which could also expand the type of science and exploration the Agents of S.H.I.E.L.D. can do. Since his arrival on the main Marvel Earth, Noh-Varr has been kidnapped, brainwashed, declared war on his new planet and eventually settled into the superhero life. He'd be able to bring the idea of non-evil Kree to the MCU and bring some much needed comedy/self-awareness.

9 Machine Man



The robot X-51 was the 51st robot created by the military as a project to create robot soldiers who could think like humans. Dr. Abel Stack then stole X-51 from the military and raised him like his own son, calling him Machine Man and creating custom made skin and hair for him. When the self-destruct sequence was activated on all these robots, Dr. Stack was killed in the process of removing Machine Man's self-destruct device. Machine Man often refers to humans as "fleshy ones" and is one sarcastic SOB. He has worked with S.H.I.E.L.D., Captain Marvel and the X-Men, in addition to taking on the Marvel Zombies universe. He was also a member of "Nextwave: Agents of H.A.T.E" -- which is something the MCU could definitely explore and please both fans of the cult-classic series and TV fans who've grown bored over the last three years. Machine Man, a character who makes jokes and is perpetually annoyed, would also be the perfect foil for Deathlok, a character who takes himself entirely too seriously.

8 Moon Girl & Devil Dinosaur



While Devil Dinosaur has been around for a while, the ongoing "Moon Girl & Devil Dinosaur" comic book is fairly new. Moon Girl, AKA Lunella Lafayette, is a 9-year-old genius with the Inhuman gene who attends school on the Lower East Side in Manhattan and was recently declared the smartest person in the Marvel Universe (dethroning Reed Richards). She encounters Devil Dinosaur after she invents a device that opens a portal to a dimension that unleashes Devil Dinosaur's enemies upon the city. Devil Dinosaur, aside from being a freaking dinosaur, has human-level intelligence (so, you know, above average for a dinosaur) that allows him to communicate with Moon Girl. Devil Dinosaur's former companion was a furry humanoid, Moon Boy, who was recently killed, with both originally hailing from a place called Dinosaur World. This team-up would be just whacky enough to work, and would also give the MCU a giant talking dinosaur. Sounds like a win-win.

7 Brother Voodoo



Jericho Drumm, also sometimes known as Doctor Voodoo, is another great supernatural character from Marvel Comics. He's a native of Haiti who got involved with mysticism after his twin brother, Daniel, died at the hands of a voodoo sorcerer. Just before his brother died, he made Jericho promise to visit his mentor, Papa Jambo, who then taught Jericho mastery of voodoo practices. And before Papa Jambo died, he bonded Jericho with the spirit of his brother Daniel and named Jericho Jambo's worthy successor. Brother Voodoo has been a member of the Avengers, and for a brief time held the title of Sorcerer Supreme (which is also when he went by Doctor instead of Brother). He's also died and come back to life at least twice -- most recently revived by Doctor Doom to fight the Scarlet Witch. He could give "Agents of S.H.I.E.L.D." a very easy tie-in storyline to the "Doctor Strange" film and bring some more diversity to the show.

6 Darkhawk



Christopher Powell was an ordinary New York teen hanging out in an abandoned amusement park before he stumbled upon a powerful amulet. He soon found out the amulet he could transfer his consciousness into the body of an android named Darkhawk. You probably remember Darkhawk as the guy who starred in his own series for 50 issues in the '90s... right? As Darkhawk, he has fought alongside the New Warriors amd Avengers (and after his heyday, the Runaways). He's been the co-star of many a comic and even played a key role in event comics like "Realm of Kings." Most recently he became one of the early victims in "Avengers Arena" (where his amulet was briefly passed on to Chase from The Runaways). He's a pretty popular B-list character (even appearing as the semi-leader in "MarvelTeam-Up:LeagueofLosers"). He'd be a great fit for the show and could function as a fantastic recurring guest star in the same way the show has previously used Deathlok and Lady Sif.

5 Man-Thing



No, not DC's Swamp Thing, but Marvel's Man-Thing. Dr. Theodore "Ted" Sallis was a biochemist working alongside Bobbi Morse (AKA Mockingbird) to recreate the Super Soldier Serum that turned Steve Rogers into Captain America. If you're thinking what we're thinking, yes, this would be a perfect excuse for the show to bring Bobbi back for an episode or two. After he was ambushed by AIM and betrayed by his fiance, Sallis injected himself with the only sample of his serum. Unfortunately, after he injection he crashed his car into a swamp -- and, due to some added magical forces it turns him into the silent, super strong (again, not Swamp Thing) Man-Thing. He also appeared with Howard the Duck and even traveled with him for a time. He also spent time as a member of the Thunderbolts and was recently recruited by Phil Coulson in the comics to join his supernatural team, the Howling Commandos of S.H.I.E.L.D.

4 Nico Minoru



Sometimes known as Sister Grimm, Nico was the leader of the Runaways and is a current member of A-Force. The daughter of two dark wizards who were part of the villainous group known as The Pride in Los Angeles, when Nico and her friends learned the truth about their parents they ran away and formed their own superhero team in defiance. Nico uses The Staff of One to cast spells, with the only catch being each can only be used once. She also appeared in "Avengers Arena" where she lost an arm and bled out -- but was resurrected by the staff itself. While "Runaways" mania has died down in the last few years, but having her appear on "Agents of S.H.I.E.L.D." would be a great way to potentially reignite interest in a possible "Runaways" series (or movie, which has also been in development at various points). This could also lead her and her Runaways team mates appearing in other MCU shows/movies. And, really, who wouldn't love seeing that?

3 Moonstone



Dr. Karla Sofen has been a member of the Thunderbolts, Dark Avengers and Masters of Evil. She's a psychologist who convinced depressed patients to kill themselves while she watched and, to add to how evil she is, also murdered her mother. She gained her powers by becoming the psychologist to the original Moonstone, Lloyd Bloch, and convincing him to reject his Moonstone gem powers, giving Dr. Sofen the opportunity to acquire them for herself. While on the Dark Avengers, she took on the identity of Ms. Marvel, and more recently she joined Winter Soldier's Thunderbolts team. She's a villain at heart, but has been known to use her powers for good every once in a while. The thought of her going toe-to-toe with Agent Melinda May -- and then a few episodes later being forced to team up with her -- is definitely an appealing one. While the show has already done the double agent twist, we think Moonstone could help it work in reverse, with a villain needing to team up with a hero for the greater good.

2 Crystal



Since Marvel's classic Inhumans can now be used on "Agents of S.H.I.E.L.D.", we look forward to seeing them arrive. Medusa, Black Bolt and Co. will be so fun to finally see on screen (even if it's just the smaller one) -- especially interacting with our favorite agents. But Crystal is one of few Inhumans who has long been associated with (or a member of) the Fantastic Four, X-Men and Avengers. She was a part of Earth's Mightiest Heroes during the '90s for a long stretch (and even wore the obligatory '90s brown leather jacket). With Quicksilver being very much dead in the MCU, we'd be interested to see who they'd pick as the father of their daughter, Luna (though Luna's inclusion isn't a requirement for getting Crystal on screen). We'd love to see her and her mightyu powers become a sometime partner to the show's agents.

1 Alpha Flight



Canada's ever popular answer to the Avengers, Alpha Flight, is a team with close ties to the X-Men. Which, clearly couldn't be addressed in the MCU what with Fox owning the live-action rights -- but Alpha Flight can exist without any X-connections. Guardian and Vindicator, Alpha Flight's leaders, are heroes who gain their powers through body armor (not unlike Iron Man). The rest of the main team consists of demi-goddess Snowbird (not unlike Thor), a scientist who can turn into a beast named Sasquatch, and a sorcerer named Shaman. Everyone's favorite Canadian superhero twins Northstar and Aurora are both, unfortunately for the MCU, mutants. But, hey, maybe they could turn them into Inhumans for the show. Then there are so many other characters they could explore like the acrobatic Puck, amphibious alien Marrina, and Shaman's daughter Talisman to name a few. It would give the show's heroes someone to team up with when traveling across the globe (or, at least, whenever they visit Canada).

Which Marvel Comics characters do you want to see make their debuts on "Agents of S.H.I.E.L.D." next season?